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. 2022 Jan 24;10(1):e004310. doi: 10.1136/jitc-2021-004310

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Major histocompatibility complex (MHC)-I and MHC–II scores were computed from bulk gene expression profiles by comparing unknown primary melanoma (MUP) tumors and known primaries. MUP had significantly higher MHC-I (p=0.004) and MHC-II (p=0.023) scores as compared with known primary.