Table a1.
Odds ratios (95% confidence intervals) for the relation of mental and physical health with later COVID-19 vaccine hesitancy in Understanding Society – with models featuring individual covariates (N = 7361).
| Number hesitant/Total at risk | Age, sex, & ethnicity | Age, sex, ethnicity, & comorbidity | Age, sex, ethnicity, & shielding | Age, sex, ethnicity, & education | Age, sex, ethnicity, and cognition | All covariates | |
|---|---|---|---|---|---|---|---|
| Psychiatric morbidity | |||||||
| Anxiety | 50/324 | 1.00 (0.72, 1.36) | 1.06 (0.76, 1.44) | 1.00 (0.72, 1.36) | 1.04 (0.74, 1.42) | 1.02 (0.73, 1.39) | 1.11 (0.79, 1.52) |
| Depression | 54/368 | 0.99 (0.72, 1.33) | 1.05 (0.77, 1.43) | 0.99 (0.72, 1.34) | 1.02 (0.74, 1.38) | 1.03 (0.75, 1.39) | 1.12 (0.81, 1.53) |
| Other mental health condition(s) | 20/111 | 1.08 (0.64, 1.75) | 1.17 (0.69, 1.89) | 1.08 (0.64, 1.75) | 1.06 (0.62, 1.73) | 1.15 (0.68, 1.87) | 1.21 (0.71, 1.97) |
| Any mental health condition | 71/491 | 0.99 (0.75, 1.29) | 1.05 (0.79, 1.37) | 0.99 (0.75, 1.29) | 1.04 (0.78, 1.35) | 1.05 (0.79, 1.37) | 1.14 (0.86, 1.49) |
| Psychological distress | |||||||
| Asymptomatic (score 0) | 443/3339 | 1.0 (ref) | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| Subclinically symptomatic (1–3) | 247/2256 | 0.77 (0.64, 0.91) | 0.77 (0.68, 0.96) | 0.77 (0.60, 0.94) | 0.79 (0.62, 0.97) | 0.79 (0.62, 0.96) | 0.81 (0.63, 0.98) |
| Symptomatic (4–6) | 90/750 | 0.77 (0.59, 0.98) | 0.78 (0.63, 1.05) | 0.77 (0.52, 1.02) | 0.78 (0.53, 1.04) | 0.78 (0.53, 1.04) | 0.82 (0.56, 1.07) |
| Highly symptomatic (7–12) | 173/1016 | 1.05 (0.85, 1.28) | 1.08 (0.91, 1.38) | 1.06 (0.86, 1.26) | 1.07 (0.87, 1.27) | 1.07 (0.86, 1.27) | 1.12 (0.92, 1.33) |
| P for quadratic | <0.0001 | 0.017 | 0.028 | 0.034 | 0.036 | 0.003 | |
| P for linear trend | 0.251 | 0.099 | 0.148 | 0.147 | 0.145 | 0.075 | |
| Per SD (3.5 points) decrease | 953/7361 | 0.93 (0.81, 1.06) | 0.91 (0.79, 1.04) | 0.92 (0.80, 1.05) | 0.92 (0.80, 1.05) | 0.92 (0.80, 1.05) | 0.88 (0.75, 1.02) |
| Physical morbidity | |||||||
| Cardiometabolic disease | 147/1905 | 0.82 (0.67, 1.00) | 0.82 (0.67, 1.00) | 0.83 (0.68, 1.01) | 0.80 (0.66, 0.98) | 0.78 (0.64, 0.95) | 0.78 (0.64, 0.95) |
| Respiratory disease | 107/1034 | 0.71 (0.57, 0.88) | 0.71 (0.57, 0.88) | 0.72 (0.58, 0.90) | 0.73 (0.58, 0.90) | 0.72 (0.57, 0.89) | 0.74 (0.59, 0.93) |
| Any cancer | 29/389 | 0.87 (0.58, 1.28) | 0.87 (0.58, 1.28) | 0.89 (0.59, 1.30) | 0.90 (0.59, 1.32) | 0.92 (0.61, 1.34) | 0.95 (0.62, 1.39) |
| Any physical health condition | 225/2389 | 0.72 (0.61, 0.85) | 0.72 (0.61, 0.85) | 0.73 (0.61, 0.86) | 0.72 (0.61, 0.85) | 0.71 (0.60, 0.83) | 0.72 (0.60, 0.85) |
| Shielding in household | 196/1383 | 0.81 (0.63, 1.03) | 0.81 (0.63, 1.03) | 0.78 (0.61, 1.00) | 0.76 (0.59, 0.97) | 0.76 (0.59, 0.96) |
All covariates are: age, sex, ethnicity, education, shielding, and cognitive function. Effect estimates for physical morbidity and psychiatric morbidity were mutually-adjusted.