Table 3.
Significant atrophy in brain regions of interest—MCI vs. CO.
| Brain Region of Interest | Mean Volume in MCI (in mm3) | Mean Volume in CO (in mm3) | Level of Significance (p) |
|---|---|---|---|
| SFG-pole left | 2000.3 | 2290.2 | 0.039 |
| STG left | 10,094.4 | 11,653.5 | 0.033 |
| STG right | 9364.7 | 10,913.4 | 0.009 |
| MTG right | 12,041.7 | 13,891.3 | 0.030 |
| MTG-pole left | 2108.6 | 2460.1 | 0.048 |
| PHG right | 1059.1 | 1208.4 | 0.038 |
| Hippocampus right | 3187.7 | 3510.2 | 0.016 |
| Basal Forebrain left | 240.9 | 277.9 | 0.059 |
| Basal Forebrain right | 225.1 | 277.2 | 0.006 |
| SCP left | 736.0 | 831.8 | 0.011 |
| Pons left | 247.1 | 284.9 | 0.029 |
| IFO left | 1642.7 | 1765.8 | 0.051 |
| Mammillary left | 80.9 | 100.0 | 0.040 |
| LFOWM right | 1523.4 | 1683.6 | 0.002 |
| RGWM left | 1556.4 | 1787.8 | 0.052 |
| STWM right | 7752.7 | 8730.2 | 0.050 |
| rostralWM-ACC left | 65.1 | 141.2 | 0.002 |
| subcallosalWM-ACC right | 60.9 | 88.9 | 0.044 |
Note: MCI indicates mild cognitive impairment; CO, control subjects.