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Opsonophagocytic killing of pneumococcus mediated by serum from mice immunized with the protein-polysaccharide conjugate vaccine. S. pneumoniae ATCC BAA334 (A) and S. pneumoniae ATCC 6308 (B). *, P < 0.05; **, P < 0.01; ***, P < 0.001. ns, not significant.