Figure 3.

Renal excretory function and plasma levels of arginine–vasopressin and renin in conscious and sevoflurane anesthetized children Urine output (mL/kg/h) (A), fractional sodium excretion (%) (B), plasma levels of arginine–vasopressin (pg/mL) (C), free water clearance (mL/min) (D), creatinine clearance (mL/min/1.73 m2) (E) and plasma levels of renin (mIE/L) (F) in children, conscious and under sevoflurane anesthesia (n = 8 with repeated measurements conscious and under sevoflurane anesthesia in the same individual). Data are expressed as mean ± standard error of the mean with the significance level set as P < .05. Within-subject pairwise comparisons between the conscious and anesthetized state were performed using Student's paired t-test. Creatinine clearance was calculated as urinary flow in mL/min * U-crea/P-crea, and then normalized according to body surface area. CH2O was calculated as urinary flow in mL/min—((U-osm/P-osm) * urinary flow in mL/min). FENa was calculated as (P-crea * U-Na)/(P-Na * U-crea), all in mmol/L.