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Electrical Restitution. (A) Two APD restitution curves, depicting the APD as a response to the preceding RR interval, of two cardiomyocytes, A (blue) and B (red, B). The slope of the APD restitution curve measures the change in APD with respect to a change in RR, and high values have been associated with increased arrhythmogenic predisposition. These changes in the APD are reflected on the ECG signal, as shown in (C).
