Figure 6.

Model simulations for the concentrations of extracellular ATP and intracellular IP₃ under control conditions. (A) Simulated extracellular ATP responses at increasing distances, in 10 µm steps, from the center of the damaged cell as indicated by the color codes in the legend. (B) First 30 sec of the traces plotted in panel A. (C) Simulated intracellular IP₃ concentrations at increasing distances in the first 30 sec post damage and in 10 µm steps from the center of the damaged cell (traces color coded as in panel A).