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(a) Protocol for Viral Integration site (VIS) barcoding studies of hematopoiesis in rhesus macaque [55, 117, 118]. Here, ‘barcodes’ are defined by the random integration sites of a lentiviral vector. (b) Xenograft barcode experiments using mice [119] in which a library of barcodes was used to tag leukemia-propagating cells before direct transplantation into mice.
