Table 2.
Demographics by type of consent in the PREMOD2 sample
| Enrolled via waiver of antenatal consent (N = 255) | Enrolled via antenatal consent (N = 219) | p-Value | |
|---|---|---|---|
| Birth GA, wk: mean (SD) | 28.3 (2.5) | 28.4 (2.4) | 0.567 |
| Compressions in delivery room | 8 (3%) | 7 (3%) | 0.921 |
| PPV in delivery room | 178 (70%) | 147 (67%) | 0.902 |
| Prenatal care | 245 (96%) | 217 (99%) | 0.058 |
| Female infant gender | 116 (45%) | 103 (47%) | 0.737 |
| Rupture of membranes duration, h: median (Q1, Q3) | 39 (7, 154) | 190 (23, 512) | <0.001 |
| Cesarean section delivery | 180 (71%) | 159 (73%) | 0.628 |
| Maternal chorioamnionitis | 90 (35%) | 63 (29%) | 0.122 |
| Full course of antenatal steroidsa | 170 (67%) | 196 (89%) | <0.001 |
| Antenatal magnesium sulfate | 207 (81%) | 184 (84%) | 0.470 |
| Apgar score at 1 min: median (Q1, Q3) | 5 (4, 7) | 6 (4, 7) | 0.504 |
| Apgar score at 5 min: median (Q1, Q3) | 8 (7, 8) | 8 (7, 9) | 0.543 |
| Oxygen at 36 wk | 46 (18%) | 47 (21%) | 0.348 |
| ROP stage 3 or more | 18 (7%) | 10 (5%) | 0.235 |
| ROP requiring treatment | 22 (9%) | 7 (3%) | 0.014 |
| PVL | 12 (5%) | 14 (6%) | 0.456 |
| Any grade IVH | 60 (24%) | 49 (22%) | 0.766 |
| Severe IVH or death | 26 (10%) | 24 (11%) | 0.788 |
| Severe IVH | 16 (6%) | 12 (5%) | 0.714 |
| Infant death | 17 (7%) | 16 (7%) | 0.785 |
Abbreviations: GA, gestational age; IVH, intraventricular hemorrhage; PREMOD2, PREmature infants receiving Milking Or Delayed cord clamping; PPV, positive pressure ventilation; PVL, periventricular leukomalacia; ROP, retinopathy of prematurity; SD, standard deviation; Severe IVH, grade III or IV intraventricular hemorrhage.
a
Full course of antenatal steroids were considered as two or more doses prior to delivery.