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. 2021 Dec 7;186(2):233–244. doi: 10.1530/EJE-21-0743

Table 2.

Adjusted hazard ratios for diabetes and diabetes death by categories of obesity and metabolic health.

MHN MHOW MHO MUN MUOW MUO
Total diabetes
 Cases 4025 3611 769 674 2859 2693
 Person-years 2 276 509 1 063 475 1 50 375 110 708 385 032 281 159
 HR, sex-adjusted 1.00 (0.97–1.03) 2.08 (2.01–2.15) 3.41 (3.17–3.66) 2.90 (2.68–3.13) 3.98 (3.84–4.13) 5.58 (5.37–5.79)
 HR, multivariable-adjusted 1.00 (0.97–1.03) 2.06 (1.99–2.13) 3.43 (3.20–3.69) 2.67 (2.47–2.88) 3.88 (3.74–4.02) 5.52 (5.31–5.73)
Type 2 diabetes
 Cases 2290 2267 460 462 1853 1701
 Person-years 2 284 124 1 068 966 151 517 111 864 389 368 285 047
 HR, sex-adjusted 1.00 (0.96–1.04) 2.39 (2.29–2.49) 3.84 (3.50–4.21) 3.41 (3.11–3.74) 4.63 (4.43–4.85) 6.50 (6.20–6.82)
 HR, multivariable-adjusted 1.00 (0.96–1.04) 2.38 (2.29–2.48) 3.97 (3.62–4.36) 3.00 (2.74–3.29) 4.49 (4.29–4.70) 6.47 (6.17–6.79)
Total diabetes death
 Cases 85 33 4 10 36 28
 Person-years 2 292 009 1 077 174 153 062 113 775 396 497 291 649
 HR, sex-adjusted 1.00 (0.80–1.25) 1.04 (0.74–1.46) 1.15 (0.43–3.07) 1.37 (0.73–2.56) 1.82 (1.31–2.52) 2.36 (1.62–3.43)
 HR, multivariable-adjusted 1.00 (0.80–1.25) 1.12 (0.80–1.58) 1.26 (0.47–3.38) 1.52 (0.81–2.84) 2.01 (1.45–2.78) 2.59 (1.78–3.76)
Type 2 diabetes death
 Cases 45 19 2 4 19 15
 Person-years 2 292 009 1 077 174 153 062 113 775 396 497 291 649
 HR, sex-adjusted 1.00 (0.74–1.36) 1.11 (0.71–1.75) 1.07 (0.27–4.30) 1.09 (0.41–2.92) 1.88 (1.20–2.94) 2.45 (1.47–4.07)
 HR, multivariable-adjusted 1.00 (0.73–1.36) 1.20 (0.77–1.89) 1.18 (0.29–4.75) 1.19 (0.44–3.19) 2.05 (1.31–3.22) 2.73 (1.64–4.55)

Sex-adjusted model: Results were adjusted for sex, age (5 years), and study region. Multivariable-adjusted HRs were adjusted for age (5 years), sex, study region, educational level (primary school or lower and middle school or higher), household income (<20 000 yuan/year or ≥20 000 yuan/year), marital status (married, others), smoking status (current regular smoker, not current regular smoker), alcohol consumption (weekly drinker, not weekly drinker), frequency of fruit intake, frequency of vegetable intake, frequency of meat intake (day/week), family history of diabetes, and physical activity (three groups).

HR, hazard ratio; MHN, metabolically healthy normal weight; MHO, metabolically healthy obesity; MHOW, metabolically healthy overweight; MUN, metabolically unhealthy normal weight; MUO, metabolically unhealthy obesity; MUOW, metabolically unhealthy overweight.