Table 2.
Adjusted hazard ratios for diabetes and diabetes death by categories of obesity and metabolic health†.
MHN | MHOW | MHO | MUN | MUOW | MUO | |
---|---|---|---|---|---|---|
Total diabetes | ||||||
Cases | 4025 | 3611 | 769 | 674 | 2859 | 2693 |
Person-years | 2 276 509 | 1 063 475 | 1 50 375 | 110 708 | 385 032 | 281 159 |
HR, sex-adjusted | 1.00 (0.97–1.03) | 2.08 (2.01–2.15) | 3.41 (3.17–3.66) | 2.90 (2.68–3.13) | 3.98 (3.84–4.13) | 5.58 (5.37–5.79) |
HR, multivariable-adjusted | 1.00 (0.97–1.03) | 2.06 (1.99–2.13) | 3.43 (3.20–3.69) | 2.67 (2.47–2.88) | 3.88 (3.74–4.02) | 5.52 (5.31–5.73) |
Type 2 diabetes | ||||||
Cases | 2290 | 2267 | 460 | 462 | 1853 | 1701 |
Person-years | 2 284 124 | 1 068 966 | 151 517 | 111 864 | 389 368 | 285 047 |
HR, sex-adjusted | 1.00 (0.96–1.04) | 2.39 (2.29–2.49) | 3.84 (3.50–4.21) | 3.41 (3.11–3.74) | 4.63 (4.43–4.85) | 6.50 (6.20–6.82) |
HR, multivariable-adjusted | 1.00 (0.96–1.04) | 2.38 (2.29–2.48) | 3.97 (3.62–4.36) | 3.00 (2.74–3.29) | 4.49 (4.29–4.70) | 6.47 (6.17–6.79) |
Total diabetes death | ||||||
Cases | 85 | 33 | 4 | 10 | 36 | 28 |
Person-years | 2 292 009 | 1 077 174 | 153 062 | 113 775 | 396 497 | 291 649 |
HR, sex-adjusted | 1.00 (0.80–1.25) | 1.04 (0.74–1.46) | 1.15 (0.43–3.07) | 1.37 (0.73–2.56) | 1.82 (1.31–2.52) | 2.36 (1.62–3.43) |
HR, multivariable-adjusted | 1.00 (0.80–1.25) | 1.12 (0.80–1.58) | 1.26 (0.47–3.38) | 1.52 (0.81–2.84) | 2.01 (1.45–2.78) | 2.59 (1.78–3.76) |
Type 2 diabetes death | ||||||
Cases | 45 | 19 | 2 | 4 | 19 | 15 |
Person-years | 2 292 009 | 1 077 174 | 153 062 | 113 775 | 396 497 | 291 649 |
HR, sex-adjusted | 1.00 (0.74–1.36) | 1.11 (0.71–1.75) | 1.07 (0.27–4.30) | 1.09 (0.41–2.92) | 1.88 (1.20–2.94) | 2.45 (1.47–4.07) |
HR, multivariable-adjusted | 1.00 (0.73–1.36) | 1.20 (0.77–1.89) | 1.18 (0.29–4.75) | 1.19 (0.44–3.19) | 2.05 (1.31–3.22) | 2.73 (1.64–4.55) |
†Sex-adjusted model: Results were adjusted for sex, age (5 years), and study region. Multivariable-adjusted HRs were adjusted for age (5 years), sex, study region, educational level (primary school or lower and middle school or higher), household income (<20 000 yuan/year or ≥20 000 yuan/year), marital status (married, others), smoking status (current regular smoker, not current regular smoker), alcohol consumption (weekly drinker, not weekly drinker), frequency of fruit intake, frequency of vegetable intake, frequency of meat intake (day/week), family history of diabetes, and physical activity (three groups).
HR, hazard ratio; MHN, metabolically healthy normal weight; MHO, metabolically healthy obesity; MHOW, metabolically healthy overweight; MUN, metabolically unhealthy normal weight; MUO, metabolically unhealthy obesity; MUOW, metabolically unhealthy overweight.