Table 1.

Mutation Rates & Classes of Mutations as determine by fluctuation analysis (Figure 2)

Pol2	URA3R (10−7)	95% CI	No. mutants	Transitions	Transversions	Insertions	Deletions
WT	0.18	0.14–0.23	211	0.04	0.06	0	0.01
D290A/E292A	3.7	3–5.6	206	0.56	2.5	0.18	0.27
N378K	7.8	4.9–12	181	1.1	6.6	0.26	0.43
Y473F	3.3	2.6–4.2	189	0.37	2.1	0.28	0.6