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Genes with mutations that induce stop codons (Q>X or S>X) in an APOBEC context (SBS2 or SBS13). Only genes with a mutation frequency of ≥ 0.5% in the metastatic setting are shown. APOBEC, Apolipoprotein B mRNA-Editing Catalytic Polypeptide-like; mBC, metastatic breast cancer; pBC, primary breast cancer; Q, glutamine; S, serine; SBS, single base-pair substitution; X, STOP (stop codon).
