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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2022 Jan 1;112(1):83–92. doi: 10.1016/j.ijrobp.2021.07.004

Table 3.

Multivariable analysis for IIEF score

Variables Variable categories Estimate Standard deviation P value

IIEF score at 6 months
 RT method 3D-CRT vs IMRT* 2.79 1.75 .11
 Age <70 vs ≥70 y* 15.04 1.63 <.001
 Race White* vs non-White 2.07 2.30 .37
 Time Baseline vs 6 mo* 5.45 0.66 <.001
 Treatment arm 3D-CRT/IMRT 70.2Gy vs 3D-CRT/IMRT 79.2Gy* −2.06 1.62 .20
IIEF score at 12 months
 RT method 3D-CRT vs IMRT* 2.29 1.55 .14
 Age <70 vs ≥70 y* 15.00 1.47 <.001
 Race White* vs non-White 4.19 2.22 .06
 Time Baseline vs 12 mo* 6.50 0.65 <.001
 Treatment arm 3D-CRT/IMRT 70.2Gy vs 3D-CRT/IMRT 79.2Gy* −1.20 1.46 .41
IIEF score at 24 months
 RT method 3D-CRT vs IMRT* −0.33 1.59 .83
 Age <70 vs ≥70 y* 14.38 1.47 <.001
 Race White* vs non-White 5.74 2.18 .009
 Salvage hormones Yes* vs No 7.19 3.13 .022
 Treatment arm 3D-CRT/IMRT 70.2Gy vs 3D-CRT/IMRT 79.2Gy* 1.59 3.74 .67
 Treatment arm*Salvage hormones −2.78 4.08 .49
 Time Baseline vs 24 months* 8.59 0.71 <.001
IIEF score at 6, 12, and 24 months
 Baseline score 0.65 0.02 <.001
 RT method 3D-CRT vs IMRT * 1.09 0.96 .25
 Age <70 vs ≥70 y* 4.69 0.94 <.001
 Race White* vs non-White 0.23 1.29 .86
 Salvage hormones Yes* vs No 2.26 2.04 .27
 Treatment arm 3D-CRT/IMRT 70.2Gy vs 3D-CRT/IMRT 79.2Gy* 2.42 2.43 .32
 Treatment arm*Salvage hormones −0.38 2.62 .89
 Time −1.91 0.35 <.001
IIEF single-item erectile dysfunction score at 6, 12, and 24 months
 Baseline score 0.56 0.02 <.001
 RT method 3D-CRT vs IMRT* 0.02 0.09 .86
 Age <70 vs ≥70 y* 0.41 0.08 <.001
 Race White* vs non-White 0.07 0.11 .53
 Time −0.17 0.032 <.001
 Treatment arm 3D-CRT/IMRT 70.2Gy vs 3D-CRT/IMRT 79.2Gy* 0.13 0.080 .093

Abbreviations: 3D-CRT = 3-dimensional conventional radiation therapy; IIEF = International I= intensity lated radiation therapy.

*

Indicates the reference level.

Single item: “How often were you able to get an erection during sexual activity?”