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. 2022 Jan 25;11:e73325. doi: 10.7554/eLife.73325

Figure 4. Relationship between T1-based diffuse fibrosis and ventricular arrhythmia (VA) inducibility in late gadolinium enhancement (LGE)-T1 and LGE-only personalized virtual-heart models of hypertrophic cardiomyopathy (HCM) patients.

Figure 4.

(A) Comparison of the number of unique VA morphologies between inducible LGE-T1 and LGE-only models for all VA-inducing pacing sites (LGE-T1: N = 14, interquartile range [IQR] = 1; LGE only: N = 12, IQR = 0.75; p = 0.0538, confidence interval [CI]: [1.25, 1.75]). (B) Correlation between amount of T1-based diffuse fibrosis and the number of unique VA morphologies induced in LGE-T1 models using logistic regression (R = 0.40, p = 0.157). (C) The distribution of the pacing sites that induced VAs in LGE-T1 and LGE-only models.

Figure 4—source data 1. Spreadsheet including source data underlying Figure 4.