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. Author manuscript; available in PMC: 2022 Jan 25.
Published in final edited form as: Neuroscience. 2002;112(2):355–365. doi: 10.1016/s0306-4522(02)00089-1

Fig. 8.

Fig. 8.

Average spike histogram before and after the cataplexy onset and offset in LC (REM-off cell) and amygdala (sleep active–cataplexy active cell). Twenty cataplexy episodes (mean duration 23.7±3.7 s) were averaged across four LC cells (Wu et al., 1999). Fifteen cataplexy episodes (mean duration 40.4±5.45 s) were averaged across three amygdala cells. The bin size of the histogram was 400 ms for both cells. Note the increased discharge in the amygdala cataplexy-on cell with reduction in muscle tone and the inverse relation between LC and amygdala cataplexy-on cells at onset and offset of cataplexy. Asterisks denote significant difference (mean±2 S.D.) in firing rate before and after the onset and offset of cataplexy episodes. Note that changes in discharge rate of amygdala cell accompany or precede changes in simultaneously recorded EMG (lowest trace).