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. 2022 Jan 20;15:77–79. doi: 10.2147/OTT.S355695

Figure 3.

Figure 3

APS enhanced the inhibition of cell invasion suppressed by apatinib.

Notes: Transwell analysis of AS PC-1 (A and B) and PANC -1 (C and D) cell invasion for 24 hours; cells were treated with control, 40 µM apatinib, 200 µg/mL APS, and 40 µM apatinib + 200 µg/mL APS. Original magnification ×100. (E) MMP-9 protein expression treated with different groups after 24 hours were determined by Western blotting. β-Actin was used as the internal control. **P<0.01, ***P<0.001 versus control; #P<0.05 versus apatinib.

Abbreviations: AP, apatinib; APS, Astragalus polysaccharide; MMP-9, matrix metalloproteinases-9.