Table 2.
Criteria of MIS-C | Case-1 | Case-2 |
---|---|---|
Age below 21 years | Yes | Yes |
Fever higher than 38°C for more than 24 hours | Yes | Yes |
Requiring hospitalization due to severe illness | Yes | Yes |
Multisystem organ involvement (more than two) | Cardiac (elevated BNP) Renal (acute kidney injury with decreased GFR) Hematological (elevated D-dimer, thrombocytopenia) Gastrointestinal (abdominal pain, vomiting) Neurological (altered mental status, headache) |
Cardiac (hypotension, shock, elevated BNP) Renal (acute kidney injury with decreased GFR) Hematological (elevated D-dimer) Gastrointestinal (abdominal pain, vomiting) |
Laboratory evidence of inflammation | Elevated levels of: | Elevated levels of: |
C-reactive protein | C-reactive protein | |
Procalcitonin | Procalcitonin | |
Fibrinogen | Fibrinogen | |
D-dimer | D-dimer | |
Neutrophilia | LDH | |
Hypoalbuminemia | Neutrophilia | |
Lymphocytopenia | ||
Current or recent SARS-CoV-2 infection, exposure within four weeks | RT-PCR (-) | RT-PCR (-) |
ELISA IgG(+), IgM(-) | ELISA IgG(-), IgM(-) | |
Exposure (+), 3 weeks previously | Exposure: unknown | |
Inconsistent findings with MIS-C | Bilateral flank pain | Right flank pain |
Bilateral CVA tenderness | Right CVA tenderness | |
Bilateral multiple hypodense renal lesions on abdomen CT. | A hypodense lesion in the right kidney on abdomen CT |
BNP – brain natriuretic peptide; CT – computed tomography; ELISA – enzyme-linked immunosorbent assay; RT-PCR – reverse transcription-polymerase chain reaction; SARS-CoV-2 – severe acute respiratory syndrome coronavirus 2.