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Table 2.

Comparison of criteria and inconsistent findings for MIS-C

Criteria of MIS-C Case-1 Case-2
Age below 21 years Yes Yes
Fever higher than 38°C for more than 24 hours Yes Yes
Requiring hospitalization due to severe illness Yes Yes
Multisystem organ involvement (more than two) Cardiac (elevated BNP)
Renal (acute kidney injury with decreased GFR)
Hematological (elevated D-dimer, thrombocytopenia)
Gastrointestinal (abdominal pain, vomiting)
Neurological (altered mental status, headache)
Cardiac (hypotension, shock, elevated BNP)
Renal (acute kidney injury with decreased GFR)
Hematological (elevated D-dimer)
Gastrointestinal (abdominal pain, vomiting)
Laboratory evidence of inflammation Elevated levels of: Elevated levels of:
C-reactive protein C-reactive protein
Procalcitonin Procalcitonin
Fibrinogen Fibrinogen
D-dimer D-dimer
Neutrophilia LDH
Hypoalbuminemia Neutrophilia
Lymphocytopenia
Current or recent SARS-CoV-2 infection, exposure within four weeks RT-PCR (-) RT-PCR (-)
ELISA IgG(+), IgM(-) ELISA IgG(-), IgM(-)
Exposure (+), 3 weeks previously Exposure: unknown
Inconsistent findings with MIS-C Bilateral flank pain Right flank pain
Bilateral CVA tenderness Right CVA tenderness
Bilateral multiple hypodense renal lesions on abdomen CT. A hypodense lesion in the right kidney on abdomen CT

BNP – brain natriuretic peptide; CT – computed tomography; ELISA – enzyme-linked immunosorbent assay; RT-PCR – reverse transcription-polymerase chain reaction; SARS-CoV-2 – severe acute respiratory syndrome coronavirus 2.