Table 2.
Comparison between the studied groups regarding hemodynamic parameters and laboratory findings (n = 90).
| Control | Minirin | Midodrine | P value | |
|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | ||
| Temperature | ||||
| 1st day of the study | 37.23 ± 0.39 | 37.2 ± 0.4 | 37.2 ± 0.62 | 0.953 |
| Midperiod of the study | 37.31 ± 0.35 | 37.34 ± 0.5 | 37.11 ± 0.39 | 0.068 |
| Last day of the study | 37.17 ± 0.25 | 37.14 ± 0.27 | 37.23 ± 0.4 | 0.541 |
|
| ||||
| Heart rate (HR) | ||||
| 1st day of the study | 120.43 ± 14.64 | 120.53 ± 11.91 | 117.5 ± 14.28 | 0.622 |
| Midperiod of the study | 97.1 ± 16.65 | 102.8 ± 20.77 | 103.77 ± 16.65 | 0.311 |
| Last day of the study | 96.73 ± 18.75 | 91.83 ± 12.71 | 79 ± 16.9 | <0.001∗∗ |
|
| ||||
| Mean arterial pressure (MAP) | ||||
| 1st day of the study | 62.87 ± 19.21 | 65.83 ± 20.29 | 52.37 ± 11.77 | 0.010∗ |
| Midperiod of the study | 83.8 ± 14.64 | 83.9 ± 11.75 | 77.17 ± 16.63 | 0.125 |
| Last day of the study | 82.57 ± 13.42 | 82.57 ± 11.94 | 77.23 ± 15.83 | 0.231 |
|
| ||||
| Respiratory rate (RR) | ||||
| 1st day of the study | 25.33 ± 6.74 | 23.6 ± 6.93 | 20.27 ± 5.6 | 0.011∗ |
| Midperiod of the study | 18.83 ± 4.19 | 17.53 ± 3.05 | 17.13 ± 3.27 | 0.157 |
| Last day of the study | 15.7 ± 3.21 | 15.57 ± 3.11 | 16 ± 3.13 | 0.862 |
|
| ||||
| Serum creatinine | ||||
| 1st day of the study | 90.35 ± 52.22 | 99.71 ± 39.97 | 63.87 ± 34.43 | 0.005∗∗ |
| Last day of the study | 123.11 ± 112.2 | 101.95 ± 41.18 | 92.12 ± 54.76 | 0.276 |
|
| ||||
| Arterial PH | ||||
| 1st day of the study | 7.41 ± 0.09 | 7.39 ± 0.08 | 7.41 ± 0.09 | 0.696 |
| Midperiod of the study | 7.42 ± 0.08 | 7.39 ± 0.08 | 7.42 ± 0.08 | 0.268 |
| Last day of the study | 7.41 ± 0.07 | 7.39 ± 0.07 | 7.41 ± 0.07 | 0.590 |
|
| ||||
| Serum HCO3 | ||||
| 1st day of the study | 19.91 ± 5.58 | 20.72 ± 7.22 | 19.91 ± 5.58 | 0.842 |
| Midperiod of the study | 21.99 ± 3.76 | 22.06 ± 8.06 | 21.99 ± 3.76 | 0.999 |
| Last day of the study | 23.14 ± 3.72 | 23.01 ± 7.05 | 22.77 ± 3.82 | 0.959 |
|
| ||||
| PO2 | ||||
| 1st day of the study | 103.37 ± 45.09 | 102.52 ± 39.24 | 103.37 ± 45.09 | 0.996 |
| Midperiod of the study | 104.07 ± 30.33 | 89.53 ± 28.56 | 104.07 ± 30.33 | 0.098 |
| Last day of the study | 82.49 ± 18.57 | 83.57 ± 23.24 | 88.32 ± 25.51 | 0.582 |
|
| ||||
| PCO2 | ||||
| 1st day of the study | 32.04 ± 9.21 | 33.5 ± 14.52 | 32.04 ± 9.21 | 0.846 |
| Midperiod of the study | 30.65 ± 6.6 | 32.33 ± 14.75 | 30.65 ± 6.6 | 0.758 |
| Last day of the study | 33.19 ± 4.52 | 32.87 ± 11.52 | 31.91 ± 5.3 | 0.803 |
One-way ANOVA tests quantitative data between the three groups or more. ∗Significant level at P value < 0.05; ∗∗significant level at P value < 0.01.