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Effect of empagliflozin on mRNA levels of genes involving in oxidative stress. Catalase, NADPH oxidase 4 (Nox4), superoxide dismutase [Cu-Zn] (Sod1), superoxide dismutase [Mn] (Sod2), metallopeptidase inhibitor type 1 (Timp1). Data are presented as mean ± standard deviation, n = 5. C: control; CE: control with empagliflozin; HF: high fat; HFE: high fat with empagliflozin. [a] ≠C; [b] ≠HF. p < 0.05; one-way ANOVA and posttest Tamhane T2.
