Table 1.
Main characteristics of study population according to SpA diagnosis.
| Total (n = 99) | SpA- (n = 63) | SpA+ (n = 36) | p value | ||||
|---|---|---|---|---|---|---|---|
| Mean ± SD/median (IQR) | N (%) | Mean ± SD/median (IQR) | N (%) | Mean ± SD/median (IQR) | N (%) | ||
| Age (yrs) | 46 ± 13 | 48 ± 12 | 43 ± 13 | 0.05 | |||
| Age < 45 yrs | 47 (48) | 25 (40) | 22 (61) | 0.04∗ | |||
| Age at uveitis diagnosis (yrs) | 42 ± 13 | 45 ± 12 | 37 ± 14 | 0.005∗∗ | |||
| Uveitis diagnostic delay (mo) | 3 (0-32) | 5 (0-36) | 1 (0-23) | 0.28 | |||
| Sex | |||||||
| M | 38 (38) | 24 (38) | 14 (38) | 0.94 | |||
| F | 61 (62) | 39 (62) | 22 (62) | ||||
| BMI (kg/m2) | 25 ± 5 | 25 ± 5 | 25 ± 6 | 0.88 | |||
| Family history of SpA† | 39 (39) | 22 (35) | 17 (47) | 0.23 | |||
| Current smoker | 23 (23) | 14 (22) | 9 (25) | 0.80 | |||
| Diabetes mellitus | 3 (3) | 2 (3) | 1 (3) | 0.91 | |||
| Dyslipidemia | 25 (25) | 16 (25) | 9 (25) | 0.75 | |||
| Hypertension | 13 (13) | 9 (14) | 4 (11) | 0.65 | |||
| HLA-B27 + | 60 (60) | 30 (48) | 30 (83) | <0.001∗∗∗ | |||
| Axial SpA | 22 (22) | 0 (0) | 22 (61) | Nd | |||
| Peripheral SpA | 14 (14) | 0 (0) | 14 (39) | Nd | |||
| IBP (ASAS criteria) | 24 (24) | 2 (3) | 22 (61) | <0.001∗∗∗ | |||
| Enthesitis | 13 (13) | 0 (0) | 13 (36) | <0.001∗∗∗ | |||
| Dactylitis | 7 (7) | 0 (0) | 7 (19) | <0.001∗∗∗ | |||
| IBD | 5 (5) | 5 (8) | 0 (0) | 0.22 | |||
| Psoriasis | 10 (10) | 7 (11) | 3 (8) | 0.66 | |||
| Urethritis/cervicitis | 12 (12) | 7 (11) | 5 (14) | 0.68 | |||
| Peripheral arthritis | 19 (19) | 0 (0) | 19 (53) | <0.0001∗∗∗ | |||
| Ophthalmic evaluation: | |||||||
| Uveitis | |||||||
| Acute | 29 (29) | 16 (25) | 13 (36) | 0.26 | |||
| Recurrent | 70 (71) | 47 (75) | 23 (64) | ||||
| Bilateral uveitis | 40 (40) | 27 (43) | 13 (36) | 0.51 | |||
| Hypopyon | 2 (2) | 0 (0) | 2 (6) | 0.06 | |||
| Synechiae | 29 (29) | 21 (33) | 8 (22) | 0.24 | |||
| Cataract | 19 (19) | 12 (19) | 7 (19) | 0.96 | |||
Legend: SD: standard deviation; IQR: interquartile range; SpA: spondyloarthritis; F: female; M: male; BMI: body max index; HLA: human leukocyte antigen; IBP: inflammatory back pain; ASAS: Assessment of SpondyloArthritis international Society; IBD: inflammatory bowel disease. †Family history of AS, psoriasis, reactive arthritis, uveitis, or IBD in a first-degree relative (father, mother, sisters, brothers, and children) or second-degree relative (maternal and paternal grandparents, aunts, uncles, nieces, and nephews).