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. 2022 Mar 8;55(3):542–556.e5. doi: 10.1016/j.immuni.2022.01.017

Figure 7.

Figure 7

Reduced cellularity is observed in the airways 1 year after initial bronchoscopy post-COVID-19

(A) % lung CT abnormality or predicted FVC (%) or TLCO (%) at first appointment and 1 year follow up (n = 17 pCOVID-19 patients).

(B) Total cell counts and cell counts of lymphocyte populations, macrophages, neutrophils, and monocyte subsets in the BAL.

(C and D) (C) Proportions of T cell subsets and (D) CD4 and CD8 CD69+ CD103+ as a proportion of BAL T cells.

(E) Proportions of memory (CD27+IgD−) and plasmablasts (CD27+CD38+) of CD20+ B cells in the BAL.

(F) DPP4, LDH, and albumin measurements in BAL. All data depict first bronchoscopy between 3–6 months post discharge and at 1 year post discharge. Each point represents a single patient. (B–E) Represent n = 3 patients. Green shading indicates median ± IQR for proportions of populations and mediator concentration observed in healthy airways. (A) Wilcoxon matched-pair signed rank test. ∗p < 0.05, ∗∗∗p < 0.001.