Table 2.
Number of patients per injection, percentage responders and adverse events
| MICCH | Comparison groups | ||
|---|---|---|---|
| Non-MICCH | ECH | ||
|
First injection (n) Clin. relevant improvement (n, %) Attack freedom (n, %) Adverse eventsa (n, %) |
47 28 (60%) 14 (30%) 15 (31%) |
22 16 (73%) 7 (32%) 5 (23%) |
49 37 (76%) 21 (43%) 11 (22%) |
|
Second injection (n) Clin. relevant improvement (n, %) Attack freedom (n, %) Adverse events (n, %) |
19 13 (68%) 3 (16%) 5 (25%) |
3 2 (67%) - 1 (33%) |
9 8 (89%) 5 (56%) 2 (22%) |
|
Third injection (n) Clin. relevant improvement (n, %) Attack freedom (n, %) Adverse events (n, %) |
9 7 (78%) 2 (22%) 1 (10%) |
2 2 (100%) 1 (50%) 1 (50%) |
- |
|
Fourth injection (n) Clin. relevant improvement (n, %) Attack freedom (n, %) Adverse events (n, %) |
3 2 (67%) 1 (33%) 2 (67%) |
1 1 (100%) - - |
- |
|
Fifth injection (n) Clin. relevant improvement (n, %) Attack freedom (n,%) Adverse events (n, %) |
2 1 (50%) 1 (50%) 1 (50%) |
1 1 (100%) - - |
- |
|
Sixth–eighth injectionb (n) Clin. relevant improvement (n, %) Adverse events (n, %) |
1 1 (50%) 1 (50%) |
- - - |
- |
aOnly minor adverse events occurred; bonly one patient received up to eight injections