Table 1.
Major differences in available medication and mechanical devices
Europe | Japan | |
---|---|---|
Glycoprotein IIb/IIIa inhibitors | Tirofiban, eptifibatide, and abciximab are available | GP IIb/IIIa inhibitors are not available |
P2Y12 inhibitors | The preferred P2Y12 inhibitors are prasugrel [60 mg loading dose and 10 mg maintenance dose once daily per os (p.o.)] or ticagrelor (180 mg p.o. loading dose and 90 mg maintenance dose twice daily) | Both prasugrel and ticagrelor are available, but the dose in prasugrel is different. [20 mg loading dose and 3.75 mg maintenance dose once daily per os] |
Mechanical LV assist devices | Intra-cardiac axial flow pump (i.e., Impella) and intra-aortic balloon pump are available | Intra-aortic balloon pumps are still in use. Intra-cardiac axial flow pumps are used in selected institutions but are not widely available |