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. 2022 Jan 12;37(1):1–34. doi: 10.1007/s12928-021-00829-9

Table 1.

Major differences in available medication and mechanical devices

Europe Japan
Glycoprotein IIb/IIIa inhibitors Tirofiban, eptifibatide, and abciximab are available GP IIb/IIIa inhibitors are not available
P2Y12 inhibitors The preferred P2Y12 inhibitors are prasugrel [60 mg loading dose and 10 mg maintenance dose once daily per os (p.o.)] or ticagrelor (180 mg p.o. loading dose and 90 mg maintenance dose twice daily) Both prasugrel and ticagrelor are available, but the dose in prasugrel is different. [20 mg loading dose and 3.75 mg maintenance dose once daily per os]
Mechanical LV assist devices Intra-cardiac axial flow pump (i.e., Impella) and intra-aortic balloon pump are available Intra-aortic balloon pumps are still in use. Intra-cardiac axial flow pumps are used in selected institutions but are not widely available