Table 2.
Major CE-approved DES and their availability in Japan
| DES | Stent platform | Polymer coating | Drug | Availability in Japan |
|---|---|---|---|---|
| Based on durable polymer coatings | ||||
| DESyne Nx | Cobalt–chrome | PBMA | Novolimus | No |
| Promus element | Platinum–chrome | PBMA and PVDF-HFP | Everolimus | Yes |
| Resolute | Cobalt–chrome | PBMA, PHMA, PVP, and PVA | Zotarolimus | Yes |
| STENTYS | Nitinol | PSU and PVP | Paclitaxel | No |
| Xience | Cobalt–chrome | PBMA and PVDF-HFP | Everolimus | Yes |
| Based on biodegradable polymer coatings | ||||
| Axxess | Nitinol | PDLLA | Biolimus A9 | No |
| Biomatrix | Stainless steel | PDLLA | Biolimus A9 | No |
| BioMime | Cobalt–chrome | PLLA and PLGA | Sirolimus | No |
| Combo | Stainless steel | PDLLA and PLGA + Additional coating with anti-CD34 | Sirolimus | No |
| DESyne BD | Cobalt–chrome | PLLA | Novolimus | No |
| Infinnium | Stainless steel | PLLA, PLGA, PCL, and PVP | Paclitaxel | No |
| MiStent | Cobalt–chrome | PLGA | Crystalline sirolimus | No |
| Nobori | Stainless steel | PDLLA | Biolimus A9 | Yes |
| Orsiro | Cobalt–chrome | PLLA | Sirolimus | Yes |
| Supralimus core | Cobalt–chrome | PLLA, PLGA, PCL, and PVP | Sirolimus | No |
| Synergy | Platinum–chrome | PLGA | Everolimus | Yes |
| Ultimaster | Cobalt–chrome | PDLLA and PCL | Sirolimus | Yes |
| Yukon choice PC | Stainless steel | PDLLA | Sirolimus | No |
| Supraflex Cruz | Cobalt–chrome | PLLA, PLGA, and PVP | Sirolimus | No |
| BuMA supreme | Cobalt–chrome | PLGA | Sirolimus | No |
| Polymer-free | ||||
| Amazonia Pax | Cobalt–chrome | – | Paclitaxel | No |
| BioFreedom | Stainless steel | – | Biolimus A9 | Yes |
| Cre8 | Cobalt–chrome | – | Sirolimus | No |
| Yukon Choice PF | Stainless steel | – | Sirolimus | No |
PBMA polyn-butyl methacrylate, PCL poly-caprolactone, PDLLA poly-D,L-lactic acid, PHMA poly-hexyl methacrylate, PLCL poly-L-lactide-co-caprolactone, PLGA poly-D,L-lactide-co-glycolide, PLLA poly-L-lactic acid, PVP polyvinylpyrrolidone, PVA polyvinyl acetate, PVDF-HFP poly-vinylidene fluoride-co-hexafluoropropylene, PSU polysulphone