Table 2.
GO biological process terms for DEGs between the control and IS groups
| GOTERM_BP | Term | PValue | Fold enrichment | Count | GeneRatio | Genes |
|---|---|---|---|---|---|---|
| 1 |
GO:0,007,165 signal transduction |
0.048507425 | 1.964164567 | 11 | 12.94117647 | CD79B, PPP4R1, IL2RB, TNFSF10, NEDD9, FLT3LG, IRS2, TNFRSF25, IQGAP1, CORO1C, SKAP2 |
| 2 |
GO:0,045,087 innate immune response |
0.001002881 | 4.339018088 | 9 | 10.58823529 | CLEC4D, CD6, DEFA4, MATK, HMGB2, EIF2AK2, S100A12, LY96, PADI4 |
| 3 |
GO:0,006,955 immune response |
0.015163648 | 3.44693704 | 7 | 8.235294118 | CD79B, NFIL3, IL1R2, TNFSF10, CCR7, TNFRSF25, CEACAM8 |
| 4 |
GO:0,006,468 protein phosphorylation |
0.02156091 | 3.182369504 | 7 | 8.235294118 | PPP4R1, TAOK1, MATK, PDK4, EIF2AK2, IRAK3, PASK |
| 5 |
GO:0,032,496 response to lipopolysaccharide |
0.001113916 | 7.584462511 | 6 | 7.058823529 | CD6, HMGB2, LY96, CCR7, IRAK3, TNFRSF25 |
| 6 |
GO:0,006,954 inflammatory response |
0.034625375 | 3.281931008 | 6 | 7.058823529 | TPST1, ORM1, S100A12, LY96, CCR7, TNFRSF25 |
| 7 |
GO:0,007,166 cell surface receptor signaling pathway |
0.041831035 | 3.783004416 | 5 | 5.882352941 | CD19, TNFSF10, LY96, EVL, TNFRSF25 |
| 8 |
GO:0,050,853 B cell receptor signaling pathway |
0.002168409 | 15.3561957 | 4 | 4.705882353 | CD79B, CD79A, PLEKHA1, CD19 |
| 9 |
GO:0,002,250 adaptive immune response |
0.033682623 | 5.60293627 | 4 | 4.705882353 | CD79B, CD79A, CLEC4D, CD6 |
| 10 |
GO:0,071,345 cellular response to cytokine stimulus |
0.004867389 | 28.26936027 | 3 | 3.529411765 | MME, LEF1, CCR7 |