Table 3.
GO molecular function terms for DEGs between the control and IS groups
| GOTERM_MF | Term | PValue | Fold enrichment | Count | GeneRatio | Genes |
|---|---|---|---|---|---|---|
| 1 |
GO:0,005,509 calcium ion binding |
0.018741709 | 2.648692469 | 9 | 10.58823529 | NELL2, ANXA3, REPS2, DYSF, S100A12, ITPR3, PADI4, IQGAP1, DSC2 |
| 2 |
GO:0,019,904 protein domain-specific binding |
0.016406406 | 5.072415865 | 5 | 5.882352941 | LAMP2, HMGB2, ID3, IRS2, IQGAP1 |
| 3 |
GO:0,016,301 kinase activity |
0.026474471 | 4.377852697 | 5 | 5.882352941 | NELL2, PRKAR1A, TAOK1, PDK4, FLT3LG |
| 4 |
GO:0,005,102 receptor binding |
0.083617609 | 2.988845609 | 5 | 5.882352941 | ABCA1, ACOX1, MATK, TNFSF10, FLT3LG |
| 5 |
GO:0,003,824 catalytic activity |
0.058139482 | 4.48962766 | 4 | 4.705882353 | HAL, MGAM, ACSL1, ECHDC3 |
| 6 |
GO:0,003,714 transcription corepressor activity |
0.069792981 | 4.157881773 | 4 | 4.705882353 | NFIL3, ID3, SAP30, AES |
| 7 |
GO:0,030,165 PDZ domain binding |
0.061420984 | 7.360901163 | 3 | 3.529411765 | SLC22A4, PLEKHA1, ACOX1 |
| 8 |
GO:0,005,522 profilin binding |
0.041348098 | 46.89166667 | 2 | 2.352941176 | VASP, EVL |
| 9 |
GO:0,050,786 RAGE receptor binding |
0.050304763 | 38.36590909 | 2 | 2.352941176 | HMGB2, S100A12 |
| 10 |
GO:0,008,301 DNA binding, bending |
0.081007285 | 23.44583333 | 2 | 2.352941176 | LEF1, HMGB2 |