Table 4.
GO cellular component terms for DEGs between the control and IS group
| GOTERM_CC | Term | P value | Fold enrichment | Count | GeneRatio | Genes |
|---|---|---|---|---|---|---|
| 1 |
GO:0,005,886 plasma membrane |
5.44E-05 | 1.895240406 | 36 | 42.35294118 | SLC22A4, SNAP23, DYSF, LY96, IRS2, ITPR3, IQGAP1, CD79B, CD79A, CD19, LAMP2, CA4, S100A12, CCR7, ABCA1, VASP, SVIL, MGAM, CD163, PLEKHA1, MME, ACSL1, ANXA3, IL1R2, KCNJ15, CKAP4, MARCKS, CLEC4D, ACOX1, VNN3, CPD, IL2RB, TNFRSF25, CEACAM8, DSC2, SKAP2 |
| 2 |
GO:0,005,737 cytoplasm |
0.08417535 | 1.287921067 | 31 | 36.47058824 | SNAP23, LEF1, HMGB2, NEDD9, ITPR3, ABHD5, IQGAP1, CORO1C, CD79B, CD79A, REPS2, S100A12, VASP, SVIL, PLEKHA1, MME, ANXA3, ARG1, IL1R2, EIF2AK2, IRAK3, PASK, RBP7, PRKAR1A, TAOK1, DPYD, ID3, EVL, PADI4, GRAP, SKAP2 |
| 3 |
GO:0,070,062 extracellular exosome |
5.30E-04 | 2.006674459 | 26 | 30.58823529 | ORM1, SNAP23, DYSF, IQGAP1, CD79B, CD19, LAMP2, CA4, TNFSF10, VASP, MGAM, PLEKHA1, MME, ANXA3, ARG1, PLXDC2, MMP9, CKAP4, RAB33B, MARCKS, CRISPLD2, TAOK1, CPD, CEACAM8, MFGE8, DSC2 |
| 4 |
GO:0,016,020 membrane |
0.001726377 | 2.070909091 | 21 | 24.70588235 | CD163, ACSL1, ANXA3, DOCK8, KCNJ15, EIF2AK2, FLT3LG, ITPR3, CKAP4, HK2, TPST1, CD6, PRKAR1A, ACOX1, CPD, IL2RB, LAMP2, CA4, EVL, FOLR3, MFGE8 |
| 5 |
GO:0,005,887 integral component of plasma membrane |
0.011315379 | 2.146525324 | 14 | 16.47058824 | ABCA1, SLC22A4, CD163, MME, KCNJ15, ITPR3, CD79B, CD79A, CD6, CD19, IL2RB, TNFSF10, TNFRSF25, CEACAM8 |
| 6 |
GO:0,005,576 extracellular region |
0.029681411 | 1.886542443 | 14 | 16.47058824 | ORM1, CD163, DEFA4, IL1R2, FLT3LG, MMP9, NELL2, CD6, CRISPLD2, TNFSF10, S100A12, TNFRSF25, FOLR3, MFGE8 |
| 7 |
GO:0,005,615 extracellular space |
0.018583106 | 2.093824018 | 13 | 15.29411765 | ORM1, ARG1, DEFA4, HMGB2, FLT3LG, LY96, MMP9, VNN3, CPD, LAMP2, TNFSF10, CEACAM8, MFGE8 |
| 8 |
GO:0,005,925 focal adhesion |
4.05E-04 | 4.99378882 | 9 | 10.58823529 | VASP, SVIL, MARCKS, MME, SNAP23, NEDD9, EVL, IQGAP1, CORO1C |
| 9 |
GO:0,009,897 external side of plasma membrane |
4.24E-04 | 7.129890454 | 7 | 8.235294118 | ABCA1, CD79B, CD79A, CD19, IL2RB, CCR7, MFGE8 |
| 10 |
GO:0,030,027 lamellipodium |
0.006143732 | 6.779761905 | 5 | 5.882352941 | VASP, DYSF, NEDD9, EVL, CORO1C |