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. 2022 Jan 25;12:1317. doi: 10.1038/s41598-022-05243-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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PDSs in breast cancer. (A) Differences in survival comparing different treatment strategies in the METABRIC/Curtis dataset. LR-p p-value calculated between TP53 groups using Log-rank test, DSS disease-specific survival. (B) PDSs compared between distinct treatment groups. (C) PDSs for breast cancer subtypes in METABRIC/Curtis dataset. (D) KM plots evaluating the association between PDS and survival in the METABRIC/Curtis dataset within PAM50 breast cancer subtypes. LR-p p-value calculated between TP53 groups using Log-rank test, Cox-p p-value calculated using Coxph regression using PDSs as continuous variable, DSS disease-specific survival.