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. 2022 Jan 25;12:1287. doi: 10.1038/s41598-022-05308-6

Table 5.

The heat shock response and the ErbB models statistics.

Heat shock response models ErbB signaling pathway models
Basic25 Refined48 Basic29 Refined29
Molecular species 10 20 110 394
Molecular reactions 17 57 242 1320
Variables 10 10 110 110
Events 17 17 242 242
Invariants 13 18 110 110
Proof obligations discharged by the default prover 79 73 794 15
Proof obligations discharged by other internal provers 0 62 154 1260

The number of variables and events is the same for the basic and the refined model. Some of the proof obligations of the refined model required another internal theorem prover than the default one to get them automatically discharged.