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. 2022 Jan 12;8:738083. doi: 10.3389/fnut.2021.738083

Table 2.

Subgroup analysis of sarcopenia for the highest vs. lowest dietary omega-3 polyunsaturated fatty acids (PUFAs) category.

Stratification Number of studies Pooled OR 95% CI P -value Heterogeneity
All studies 5 0.41 0.26, 0.65 P <0.001 P = 0.03; I2 = 60%
Geographical region
   Asia 3 0.33 0.13, 0.80 P = 0.01 P = 0.02; I2 = 71%
   Non-Asia 2 0.53 0.44, 0.65 P <0.001 P = 0.28; I2 = 13%
Gender
   Male 2 0.58 0.23, 1.47 P = 0.25 P = 0.07; I2 = 69%
   Female 1 0.25 0.11, 0.54 / /
Sample size
   <500 2 0.28 0.06, 1.45 P = 0.13 P = 0.04; I2 = 76%
   >500 3 0.41 0.21, 0.77 P = 0.006 P = 0.06; I2 = 59%
Exposure assessment
   FFQ 4 0.35 0.18, 0.67 P = 0.002 P = 0.04; I2 = 61%
   24 h recall 1 0.55 0.45, 0.67 / /
Diagnostic criteria of sarcopenia
   AWGS 2 0.42 0.17, 1.05 P = 0.06 P = 0.03; I2 = 71%
   Other 3 0.38 0.19, 0.75 P = 0.005 P = 0.07; I2 = 62%
Adjustment of BMI
   Adjusted 3 0.41 0.21, 0.77 P = 0.006 P = 0.06; I2 = 59%
   Unadjusted 2 0.28 0.06, 1.45 P =0.13 P = 0.04; I2 = 76%
Adjustment of physical activity
   Adjusted 2 0.52 0.30, 0.91 P = 0.02 P = 0.05; I2 = 68%
   Unadjusted 3 0.28 0.16, 0.51 P <0.001 P = 0.37; I2 = 0%
Adjustment of energy intake
   Adjusted 3 0.38 0.19, 0.75 P = 0.005 P = 0.07; I2 = 62%
   Unadjusted 2 0.42 0.17, 1.05 P = 0.06 P = 0.03; I2 = 71%
Adjustment of co-morbidities
   Adjusted 3 0.35 0.16, 0.78 P = 0.01 P = 0.02; I2 = 70%
   Unadjusted 2 0.54 0.44, 0.66 P <0.001 P = 0.25; I2 = 24%