Table 2.

Clinical, imaging and CSF AD variables from the parent trial, and newly analyzed CSF vascular, inflammatory and immune markers.

Cognitive and functional tests	Imaging measures	CSF Aβ, Tau and P-tau 181	Vascular markers	Inflammation and immune markers
ADL	Deep WMHV	Aβ 40	CRP	IL-1α	Eotaxin
ADAS-Cog13	Global WMHV	Aβ 42	ICAM1	IL-1β	Eotaxin-3
CDR-SOB	Entorhinal GMV	P-tau 181	SAA	IL-2	IP-10
Memory composite	Hippocampal GMV	T-tau	VCAM-1	IL-5	MCP-1
	Temporal-parietal GMV meta-ROI	Aβ 42/40 ratio	BFGF	IL-6	MCP-4
		Aβ 42/T-tau	FLT-1	IL-7	MDC
			PIGF	IL-8	MIP-1α
			Tie-2	IL-10	MIP-1β
			VEGF-C	IL-13	TARC
			VEGF-D	IL-17A	IL12:IL23p40
			VEGF	IL-15	IFN-γ
				IL-16	TNF-α
					TNF-β