Table 1.

Effect of RA on CP-induced changes in kidney function markers.

Parameter	CON	Group CP	CP + RA100	RA100
BUN	1.00	4.16 ± 0.31***	3.00 ± 0.36#	0.94 ± 0.08
Creatinine	1.00	3.11 ± 0.32***	1.47 ± 0.16#	1.03 ± 0.13

All the data were calculated as fold values as compared with each group. CP-treated animals showed significantly (***p < 0.001) higher levels of BUN and serum Cr when compared with control group of animals. However, treatment with RA at the dose of 100 mg/kg significantly (^#p < 0.05) reduces the level of BUN and Cr in CP + RA100 group of animals when compared with CP group of animals. No significant changes in the level of BUN and serum Cr were observed in RA100 treated group of animals vs. controls (n = 6).