Table 2.
Correlation between clinical pain changes (VAS) (active minus baseline) and baseline BOLD signal variability (SDBOLD).
| Frequency band | Brain region | MNI coordinates (x, y, z) |
Number of voxels | R-value |
|---|---|---|---|---|
| Slow-5 (0.01–0.027 Hz) |
R vmPFC | 10 48 −10 | 172 | −0.95 |
| R thalamus | 2 −8 8 | 306 | 0.88 | |
| L cerebellum | −8 −72 −38 | 249 | 0.88 | |
| Slow-4 (0.027–0.073 Hz) |
L vmPFC | −4 62 −4 | 180 | −0.89 |
| R parahippocampal gyrus | 14 −36 −10 | 220 | 0.89 |
All statistical results were thresholded at voxel-level Z > 2.3 and cluster-level p < 0.025, FWE-corrected. vmPFC, ventromedial prefrontal cortex; rACC, rostral anterior cingulate cortex; pINS, posterior insula; MCC, midcingulate cortex; SMA, supplementary motor area. L, left; R, Right.