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. 2022 Jan 12;12:803490. doi: 10.3389/fmicb.2021.803490

FIGURE 7.

FIGURE 7

Results of the fermentation of integrated engineered strains to produce baccatin III. Baccatin III production has undergone two stages of improvement. Stage 1, Semi-rational design in improving thermostability of DBAT; Stage 2, Metabolic engineering strategy in improving acetyl-CoA supply.