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. 2022 Jan 12;8:808391. doi: 10.3389/fmed.2021.808391

Table 1.

Characteristics of the included studies.

Study Year Design study Area Infection group Non-infection group Risk factors
Stang et al. (8) 2002 Case-control USA 26 137 01.02.03.07.20.21.22.24
Hanes et al. (9) 2006 Cohort France 30 60 01.02.07.08.09.11.14.15.16.17.18.21.22.23.24.25
Nseir et al. (10) 2011 Case-control China 35 140 01.02.04.11.14.15.16.19.21.23
Xu et al. (11) 2012 Case-control Germany 36 28 01.02.03.08.09.10.12.13.14.15.17.18
Guo et al. (12) 2014 Case-control China 42 84 01.02.04.06.08.09.11.14.15.16.19
Saugel et al. (13) 2016 Case-control Netherlands 6 15 01.02.03.08.09.10.11.13.14.16
Ibn Saied et al. (14) 2019 Case-control China 29 58 01.02.03.09.10.11.13.14.17.18.21.22.23.24.25
Lei et al. (15) 2020 Case-control USA 102 1,492 01.02.05.06.07.11.12.13.20

01, Age, years; 02, Gender; 03, APACHE-II score; 04, APACHE-II score >20; 05, Glasgow score; 06, Glucocorticoid; 07, Length of ICU stay, days; 08, COPD; 09, Diabetes; 10, Malignancy; 11, Cardiovascular disease; 12, kidney dysfunction; 13, Immunosuppression; 14, Mechanical ventilation; 15, Tracheal intubation; 16, Tracheotomy; 17, Central venous catheterization; 18, Urinary catheter; 19, Nasogastric tube; 20, Operation; 21, Carbapenems; 22, β-lactamase inhibitor; 23, Aminoglycosides; 24, Quinolones; 25, Nitroimidazoles.