Table 2.

Summary of Protein Mutations and Scores in Sc1, Sc2, and Cr Data Set

	Type	Number	Max Score	Min Score
Sc1	Single aa substitution	1,015	5.22	−14
	Duplication	5	0.57	−3.74
	Deletion	71	0.81	−4,000
	Insertion	2	1.64	−4.78
	Complex	37	−0.75	−2,650
Sc2	Single aa substitution	721	7.37	−14
	Duplication	24	2.08	−9.54
	Deletion	62	−1.48	−5,978
	Insertion	1	−0.17	−0.17
	Complex	61	4.07	−2,910
Cr data set	Single aa substitution	1,263	5.18	−12.7
	Duplication	27	1.5	−6.84
	Deletion	74	0.58	−4,259
	Insertion	19	1.83	−8
	Complex	141	1,343	−6,620

Note.—Complex mutations refer to cases where more than one kind of mutation (substitution, insertion, or deletion) occur in the same protein.