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Representative abnormalities identified in the valves of the patients of this study. Aortic insufficiency (A) and aortic stenosis (B) in a female in the age range of 26–30 years with MPS IVA, who also had a reduced ejection fraction (35%). Mitral insufficiency (C) in a male in the age range of 21–25 years with MPS VI. Mitral stenosis (D) in an adolescent male with MPS II.
