Table 2.
Characteristics of the subjects according to the age group.
| Overall (n = 76) | Children (n = 53) | Adults (n = 23) | p-value | |
|---|---|---|---|---|
| Sex (n) | M: 46 F: 30 |
M: 34 F: 19 |
M: 12 F: 11 |
0.444 |
| Age (years) | 11.3 (12.7) | 9.2 (7.3) | 26.7 (9.8) | <0.001† |
| Weight (kg) | 25.6 (21.0) | 21.5 (10.0) | 40.0 (32.0) | <0.001† |
| Height (cm) | 111.0 (35.0) | 104.0 (22.0) | 128.5 (42.0) | <0.001† |
| BSA (m2) | 0.9 (0.5) | 0.80 (0.29) | 1.21 (0.62) | <0.001† |
| Treated with ERT (n) | 47/76* | 32/53* | 15/23 | 0.799 |
| Age at the start of ERT (years) | 8.3 (10.1) | 6.3 (6) | 17.1 (6.25) | <0.001† |
| Time on ERT (months) | 41.0 (77.0) | 33.5 (58) | 107.06 (65) | <0.001† |
Continuous variables are reported as median and interquartile range.
*
Four children who received ERT as a concomitant therapy for HSCT are not included in the ERT-treated group. Statistical analysis with chi-squared for categorical variables and Mann-Whitney U test for continuous variables.
†
p < 0.05.