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. 2022 Jan 12;12:752512. doi: 10.3389/fmicb.2021.752512

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Copyright © 2022 Li, Li, Ni, Zhang, Jia, Wu, Sun and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of diet type, berberine, and antibiotic treatment on the composition of gut microbiota in mice. (A) Proportion of dominant phyla; (B) Influence of different diets and berberine and antibiotic treatments on the relative abundance of the dominant phyla; (C) PCoA ranking results based on OTU composition; (D) Changes in the relative abundance of dominant genera of gut microbiota in mice under different diet and berberine and antibiotic treatments. HFD, high fat diet group; HFDBBR, HFD supplemented with berberine; HFDABT, HFD supplemented with antibiotics (by drinking freely); HFDABTBBR, HFD supplemented with berberine and antibiotics; NCD, normal chow diet; and NCDBBR, NCD supplemented with berberine. Different letters on the right side of the bars in (B) indicate significant differences. *p < 0.05; ***p < 0.001.