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. 2022 Jan 12;9:795600. doi: 10.3389/fcell.2021.795600

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Copyright © 2022 Xie, Zou, Ye, Zhao, Xie, Ou, Xie and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Extra test of the risk signature in the METABRIC cohort and a GEO neoadjuvant therapy cohort (GSE25066). (A) Distribution of the adjusted risk score and heatmap in the METABRIC cohort. (B) PCA plot based on the risk score in the METABRIC cohort. (C) Kaplan–Meier survival analysis of the low- and high-risk group patients in the METABRIC cohort. (D) ROC curve analysis according to the 1-, 2-, 3-, 4-, and 5-year survival of the AUC value in the METABRIC cohort. (E) Comparison of the enrichment scores of 22 types of immune cells between low- (blue) and high-risk (red) groups in the METABRIC cohort. (F) ROC curve analysis for predicting the response of neoadjuvant therapy in the GEO neoadjuvant therapy cohort (GSE25066).