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. 2022 Jan 20;12(1):32–42. doi: 10.5662/wjm.v12.i1.32

Table 3.

Organ procurement and transplantation network imaging classification for class 5 lesions in patients with cirrhosis

OPTN class
Description
Comments
0 Incomplete are technically in adequate study No MELD exception points
5A Lesion size ≥ 1 cm and ≤ 2 cm Increased contrast enhancement in the late hepatic arterial phase along with either: (1) Wash out during late contrast phases and peripheral rim enhancement (capsule or pseudocapsule); and (2) Biopsy consistent with HCC
5A-g Lesion size ≥ 1 cm and ≤ 2 cm Increased contrast enhancement in the late hepatic arterial phase along with growth ≥ 50% documented on serial CT or MR obtained ≤ 6 mo apart
5B Lesion size ≥ 2 cm and ≤ 5 cm Increased contrast enhancement in the late hepatic arterial phase along with either: (1) Wash out during late contrast phases; (2) Peripheral rim enhancement (capsule or pseudocapsule); (3) Growth ≥ 50% documented on serial CT or MR obtained ≤ 6 mo apart in the absence of ablative therapy; and (4) Biopsy consistent with HCC
5T Prior local regional therapy for HCC Any residual lesion or perfusion defect at the site of prior class 5A, 5A-g, 5B lesion

OPTN: Organ procurement and transplantation network; MELD: Model for end-stage liver disease; HCC: Hepatocellular carcinoma.