Table 4.
Drugs
|
Source of exosomes
|
Animal model (Yes/No)
|
Clinical sample (Yes/No)
|
Functions
|
Ref.
|
Norcantharidin | BMSCs-exosomes | Y | N | Induce cell cycle arrest, reduced tumor cell proliferation, increased apoptosis | [67] |
siGRP78 | BMSCs-exosomes | Y | N | Sensitize Sorafenib resistant cancer cells to Sorafenib | [68] |
miR-214 | hCEC-exosomes | N | Y (n = 6) | Enhances the anti-tumor efficacy of oxaliplatin and sorafenib on HCC cells | [69] |
BMSCs: Bone marrow mesenchymal stem cell; hCEC: Human cerebral endothelial cell; HCC: Hepatocellular carcinoma.