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. 2022 Jan 15;14(1):334–347. doi: 10.4251/wjgo.v14.i1.334

Table 4.

As a carrier for drug treatment

Drugs
Source of exosomes
Animal model (Yes/No)
Clinical sample (Yes/No)
Functions
Ref.
Norcantharidin BMSCs-exosomes Y N Induce cell cycle arrest, reduced tumor cell proliferation, increased apoptosis [67]
siGRP78 BMSCs-exosomes Y N Sensitize Sorafenib resistant cancer cells to Sorafenib [68]
miR-214 hCEC-exosomes N Y (n = 6) Enhances the anti-tumor efficacy of oxaliplatin and sorafenib on HCC cells [69]

BMSCs: Bone marrow mesenchymal stem cell; hCEC: Human cerebral endothelial cell; HCC: Hepatocellular carcinoma.