Table 2.
Helicobacter pylori infection effect in whole gastroenterology tract malignant diseases
|
Site
|
Malignant cell type
|
H. pylori
effect
|
Odds ratio
|
95%CI
|
P
value
|
Gastrointestinal transit time
|
| Oral cavity | Squamous cell carcinoma | Non related | 1 min | |||
| Pharynx-larynx | Squamous cell carcinoma | Increased risk1 | 2.87 | 1.71-4.84 | < 0.05 | 1 s |
| Oesophagus | Squamous cell carcinoma | Non related | 4-8 s | |||
| Adenocarcinoma | Protected effect | 0.56 | 0.46-0.68 | < 0.05 | ||
| Stomach | Adenocarcinoma | Cause-effect | 5.9 | 3.4-10.3 | < 0.05 | 2-4 h |
| MALT lymphoma | Cause-effect | 1.96 | 1.0-3.9 | < 0.05 | ||
| Small intestine | Lymphoma | Non related | 6 h | |||
| Colorectum | Adenocarcinoma | Partial cause-effect | 1.7 | 1.64-1.76 | < 0.05 | 10 h to days |
| Lymphoma | Non related |
1
Influence of smoking and alcohol consumption on Helicobacter pylori and laryngeal carcinoma was not removed from their study. CI: Confidence interval; MALT: Mucosa-associated lymphoid tissue; H. pylori: Helicobacter pylori.