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. 2022 Jan 15;14(1):216–229. doi: 10.4251/wjgo.v14.i1.216

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Overview of interactions between gastric cancer cells and various immune cells. PD-L1: Programmed death-ligand 1; TGF: Transforming growth factor; IL: Interleukin; TNF: Tumor necrosis factor; MDSC: Myeloid-derived suppressor cell; GC: Gastric cancer; NK: Natural killer; TAMs: Tumor-associated macrophages; IFN: Interferon; GZM: Granzyme; Treg: Regulatory T cell; Breg: Regulatory B cell; MMP: Matrix metalloproteinase; EGF: Epidermal growth factor.