Table 2.
FT-IR functional groups present at various vibrational frequencies (Wave numbers/cm−1).
| Formulation | Frequencies | Functional Group |
|---|---|---|
| NAC (Drug) | 2549 cm−1 | SH stretching |
| 3372 cm−1 | N–H band | |
| 1184 cm−1 | C–N stretching | |
| 1535 cm−1 | N–H stretching vibrations of NH group | |
| 1450 cm−1. | CH3 group | |
| PLGA (Polymer) | 1715 cm−1 | C=O carboxylic group |
| 2996 cm−1 | Alkyl groups | |
| 1751 cm−1 | Carbonyl stretching group | |
| 1100-1176 cm−1 | Ester group | |
| NAC-PLGA-F127 (Physical Mixture) | 2996 cm−1 | Alkyl groups |
| 1751 cm−1 | Carbonyl stretching group | |
| 1100-1176 cm−1 | Ester group | |
| 1345 cm−1, 1298 cm−1, 1249 cm−1, and 952 cm−1 | CH2 stretching vibration | |
| NAC-PLGA-MPPs (Formulation) | 1560 cm−1 | Amide I |
| 1530 cm−1 | Amide II | |
| 1275-1370 cm−1 | Amide III | |
| 1535 cm−1 | N–H stretching vibrations of NH group | |
| 1120 cm−1 | C–O stretching band |