. 2022 Jan 12;8:808106. doi: 10.3389/fnut.2021.808106

Table 4.

Effect of common EOs and MEEOs on the relative mRNA expressions of pro-inflammatory cytokine and toll-like receptor in the duodenum, jejunum and ileum of weaning piglets.

Item	Group¹						SEM²	P-Value
	Con	CTC	LEO	HEO	LMEEO	HMEEO
Duodenum
IL-1β	1.00	1.11	0.79	1.61	0.66	0.96	0.12	0.263
IL-6	1.00	0.68	0.70	0.83	0.83	1.21	0.08	0.324
IL-8	1.00^b	0.94^b	0.63^b	3.21^a	0.77^b	1.55^b	0.23	0.005
TNF-α	1.00^b	0.74^b	0.80^b	2.29^a	0.47^b	0.53^b	0.14	<0.001
TLR4	1.00^b	1.26^b	0.53^b	2.87^a	0.88^b	1.68^b	0.19	0.004
TLR8	1.00^b	0.63^b	1.25^ab	2.09^a	0.57^b	0.39^b	0.16	0.017
Jejunum
IL-1β	1.00^b	1.25^b	2.55^a	1.14^b	0.90^b	0.28^b	0.20	0.029
IL-6	1.00	0.66	0.79	0.82	0.74	1.06	0.07	0.591
IL-8	1.00	0.86	1.02	0.39	0.35	0.78	0.09	0.077
TNF-α	1.00	0.97	1.36	0.88	0.46	0.57	0.11	0.242
TLR4	1.00	1.06	1.67	0.97	0.57	0.42	0.13	0.101
TLR8	1.00	1.15	1.99	1.59	1.63	1.10	0.16	0.406
Ileum
IL-1β	1.00^bc	1.64^ab	1.40^b	2.61^a	0.33^c	0.62^bc	0.17	<0.001
IL-6	1.00	0.88	0.97	1.44	1.02	1.20	0.06	0.073
IL-8	1.00	2.29	1.64	2.34	1.10	1.08	0.19	0.093
TNF-α	1.00^b	2.27^b	1.64^b	4.66^a	0.86^b	1.02^b	0.28	<0.001
TLR4	1.00^b	2.35^b	2.2^b	5.60^a	0.85^b	0.98^b	0.33	<0.001
TLR8	1.00^b	2.99^b	3.19^b	15.55^a	1.56^b	1.36^b	0.95	<0.001

IL, interleukin; TNF-α, tumor necrosis factor-α; TLR, toll-like receptors.

^{a, b, c}

Values with different letters were significantly different (P <0.05).

Con, basal diet; CTC, basal diet supplemented with 75 mg/kg chlortetracycline; LEO, basal diet supplemented with 100 mg/kg common EOs; HEO, basal diet supplemented with 500 mg/kg common EOs; LMEEO, basal diet supplemented with 100 mg/kg MEEOs; HMEEO, basal diet supplemented with 500 mg/kg MEEOs.

SEM means standard error of the means (n = 8).