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. 2022 Jan 12;12:768130. doi: 10.3389/fgene.2021.768130

TABLE 1.

Relative expression of TSGs and genes related to migration and metastasis. The values are taken as mean of three experiments ±SD (p ≤ 0.05).

Genes Gene ensemble no. Gene information RQ chrysin 10 µM RQ chrysin 15 µM
IL2 Hs00174114_m1 Interleukin 2 0.04 0.02
MMP9 Hs00234579_m1 Matrix metallopeptidase 9 0.07 0.06
WNT1 Hs00180529_m1 Wnt family member 1 0.11 0.07
FOS Hs00170630_m1 Fos proto-oncogene 0.20 0.18
MYC Hs99999003_m1 Myelocytomatosis viral oncogene homolog 0.20 0.10
JUN Hs99999141_s1 Jun proto-oncogene 0.20 0.17
MTA1 Hs00183042_m1 Metastasis associated 1 0.26 0.14
MTA2 Hs00191018_m1 metastasis associated 2 0.28 0.14
MMP14 Hs01037009_g1 matrix metallopeptidase 14 0.31 0.25
SNAIL1 Hs00195591_m1 Snail family transcriptional repressor1 0.35 0.27
SMAD4 Hs00232068_m1 SMAD family member 4 0.36 0.12
SNAIL2 Hs00161904_m1 Snail family transcriptional repressor2 0.38 0.23
CXCL8 Hs99999034_m1 C-X-C motif chemokine ligand 8 0.41 0.12
IL6 Hs00174131_m1 Interleukin 6 0.42 0.10
SMAD3 Hs00969210_m1 SMAD family member 3 0.43 0.15
TGFβ1 Hs00998133_m1 Transforming growth factor beta 1 0.44 0.16
IL1A Hs00174092_m1 Interleukin 1 alpha 0.46 0.10
ESR1 Hs01046816_m1 Estrogen receptor 1 metastasis associated 2 0.47 0.03
TWIST1 Hs00361186_m1 Twist family bHLH transcription factor 1 0.49 0.24
MMP2 Hs00234422_m1 Matrix metallopeptidase 2 0.55 0.22
FOSL1 Hs04187685_m1 1FOS-like 1 0.58 0.36
PTEN Hs01920652_s1 Phosphatase and tensin homolog 1.48 4.41
CDH1 Hs00170423_m1 Cadherin 1 1.50 2.40
TP53 Hs01034249_m1 Tumor protein p53 1.60 2.50
FHIT Hs00896860_m1 Fragile histidine triad 1.70 3.60
RASSF1 Hs00945255_g1 Ras association domain family member 1 2.08 4.20
SOCS1 Hs00705164_s1 Suppressor of cytokine signaling 1 2.20 4.50
TIMP4 Hs00162784_m1 TIMP metallopeptidase inhibitor 4 2.50 3.20
RARB Hs00977140_m1 Retinoic acid receptor beta 2.80 6.70
TIMP3 Hs00165949_m1 TIMP metallopeptidase inhibitor 3 3.70 4.40