TABLE 3.
RQ values of chromatin-modifying enzymes after chrysin treatment. The values are taken as mean of three experiments ±SD (p ≤ 0.05).
| Gene information | Genes | RQ chrysin 10 µM | RQ chrysin 15 µM |
|---|---|---|---|
| Class II major histocompatibility complex transactivator | CIITA | 2.80 | 7.90 |
| SET domain containing | SETD2 | 2.70 | 4.90 |
| Establishment of sister chromatid cohesion N-acetyltransferase 2 | ESCO2 | 2.20 | 7.80 |
| Histone deacetylase IV | HAT 1 | 0.50 | 0.32 |
| Wolf–Hirschhorn syndrome candidate 1 gene | WHSC1 | 0.49 | 0.17 |
| A member of NF2/ERM/4.1 superfamily | EHM2 | 0.44 | 0.02 |
| Histone deacetylase 2 | HDAC 2 | 0.42 | 0.15 |
| Histone deacetylase 1 | HDAC 1 | 0.41 | 0.13 |
| Aurora kinase C | AURKC | 0.40 | 0.30 |
| DNA methyl transferase 1 | DNMT1 | 0.39 | 0.09 |
| DNA methyl transferase 3A | DNMT3A | 0.38 | 0.34 |
| DNA methyl transferase 3B | DNMT3B | 0.37 | 0.03 |
| Aurora kinase B | AURKB | 0.36 | 0.08 |
| Aurora kinase A | AURKA | 0.34 | 0.11 |
| Protein Arginine methyltransferase 8 | PRMT8 | 0.34 | 0.20 |
| Histone deacetylase 11 | HDAC 11 | 0.26 | 0.03 |
| Histone deacetylase 4 | HDAC 4 | 0.25 | 0.12 |
| A SH1-like histone lysine methyltransferase | ASH1L | 0.23 | 0.02 |
| Ubiquitin-specific peptidase 22 | USP22 | 0.14 | 0.05 |
| Histone deacetylase 3 | HDAC 3 | 0.52 | 0.11 |
| Ubiquitin-specific peptidase 21 | USP21 | 0.09 | 0.01 |