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. 2022 Jan 11;8(1):e29745. doi: 10.2196/29745

Table 3.

Blended psychological interventions.

Therapy and authors Cancer Study design Intervention Results
Traditional CBTa

van de Wal et al [47,63,71] BCb, PCc, or colorectal; survivors; BC, PC, and CRCd Study protocol; RCTe; RCT The SWORDf study: 5 individuals 1-hour F2Fg sessions+three 15-minute web-based sessions based on traditional CBT; UCh
  • SWORD had a greater effect on FCRi than UC with a moderate-to-large effect size (Cohen d=0.76).

  • SWORD had a greater effect on FCR than UC (mean difference −1.787, 95% CI −3.251 to − 0.323; P=.02) at the 15-month follow-up.


van de Wal et al [41] Survivors of BC Case study The SWORD study: 7 F2F therapy sessions and 1 telephone session based on traditional CBT
  • CBT reduced FCR over time (last follow-up at 12 months after therapy).


Luigjes-Huizer et al [72] j Study protocol BLANKETk: 2 CBT modules+5 optional modules; UC

Leermakers et al [73] Survivors of CRC Study protocol CORRECTl: 5 F2F sessions +3 telephone sessions and an interactive self-management website; UC

Döking et al [74] Survivors of CRC Case study CORRECT for 4 months: 5 F2F+3 telephone sessions and an interactive self-management website
  • The intervention was successful in reducing the distress of a survivor of cancer.

Contemporary CBT

Lyhne et al [75] Survivors of CRC Study protocol Therapist-guided iConquerFear: 5 modules; UC

aCBT: cognitive behavioral therapy.

bBC: breast cancer.

cPC: prostate cancer.

dCRC: colorectal cancer.

eRCT: randomized controlled trial.

fSWORD: Survivors’ Worries of Recurrent Disease.

gF2F: face to face.

hUC: usual care.

iFCR: fear of cancer recurrence.

jThe type of cancer was not specified.

kBLANKET: blended care for fear of cancer recurrence.

lCORRECT: colorectal cancer distress reduction.